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Oxygen is an essential nutrient for life. Yet, excessive combinations of certain forms of reactive oxygen species—known as free oxygen radicals—can result in cell mutations and cell death. Indeed, many diseases have been linked to free oxygen radicals and cell apoptosis, including adult respiratory distress syndrome, heart attack, stroke, Parkinson’s disease, and complications associated with organ transplantation. Additionally, it has been shown that the harmful effects of exposure to toxic chemicals and radiation are directly related to generation of free oxygen radicals and cell death.

Substantial efforts have been devoted to developing antioxidants and anti-apoptotic drugs. Despite some success, there are no commercial products that are highly effective, non-toxic, inexpensive to manufacture, and can be tuned to possess other desirable properties such as the ability to cross the blood-brain barrier.

Tego Biosciences has developed a new class of therapeutics. Tego’s strategy is to initially commercialize products for imaging central nervous system disorders. Tego is also developing products to reduce the side effects of radiation therapy and chemotherapy and mitigate complications associated with organ transplantation and tissue engineering.
 

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